Pediatric Immunization Advancement
Pannaraj Lab
In the News
In the News
"In the midst of all the confusion, parents and patients now must advocate for themselves. But we are here to help. We are here for you.
Ask your pediatricians to help you find the right answers for your child.
We are all in this together for every child and for our community."
-Dr. Pia Pannaraj
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Selected Publications:
Engstrom EE, Kaplan SL, Barson WJ, Lin PL, Dahl S, Bradley JS, Pannaraj PS, Tan TQ, Dien Bard J, Ramirez K, Grant LR, Arguedas A, Tort MJ, Miller A, Cané A, Hulten KG. Pneumococcal Pneumonia in Hospitalized Children: 2017-2023. Pediatrics. 2026 May 1;157(5):e2025073196. PMID: 42036116
Nicols AR, Lee Y, Congrave-Wilson Z, Kim M, Cheng WA, Jumarang J, Navarro J, Navarro R, Rodriguez-Angeles Y, Durand D, Taylor ZW, De León RG, Ochoa TJ, Sette A, da Silva Antunes R, Pannaraj PS. Peripheral rotavirus-specific T-cell responses following monovalent oral rotavirus vaccine in infants. NPJ Vaccines 2026 Mar 5;11(1):83. PMID:41786777
Chwa JS, Kim M, Lee Y, Cheng WA, Shin Y, Jumarang J, Bender JM, Pannaraj PS. Detection of SARS-CoV-2 Specific Secretory IgA and Neutralizing Antibodies in Nasal Secretions of Exposed Seronegative Individuals. Viruses 2024;16(6):852. PMID: 38932145
Chwa JS, Shin Y, Lee Y, Fabrizio T, Congrave-Wilson Z, Cheng WA, Jumarang J, Kim M, Webby R, Bender JM, Pannaraj PS. SARS-CoV-2 Variants May Affect Saliva RT-PCR Assay Sensitivity. J Appl Lab Med. 2024 Sep 9. Online ahead of print. PMID: 39246012
Parker RS, Le J, Villa M, Luong A, Lin TY, Lee Y, Doan A, Aguayo-Hiraldo P, Pannaraj PS, Yoon SJ, Wallace WD, Armstrong A, O'Gorman MR, Bard JD, Parekh C. COVID-19 vaccinated children, adolescents, and young adults with acute lymphoblastic leukemia show spike reactive antibodies and multifunctional T-cells. Int J Cancer. 2024 Jul 15. Online ahead of print. PMID: 39005114
Zambrano LD, Newhams MM, Simeone RM, Payne AB, Wu M, Orzel-Lockwood AO, Halasa NB, Calixte JM, Pannaraj PS, …Campbell AP, Randolph AG. Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron–Associated Hospitalization in Children and Adolescents — United States, 2021–2023. MMWR Morb Mortal Wkly Rep 2024;73:330–338. PMID: 38635481
Kim M, Cheng WA, Congrave-Wilson Z, Ruiz CJM, Turner L, Mendieta S, Jumarang J, Del Valle J, Lee Y, Fabrizio T, Allen EK, Thomas PG, Webby R, Gordon A, Pannaraj PS. Comparisons of Pediatric and Adult SARS-CoV-2-Specific Antibodies up to 6 Months after Infection, Vaccination, or Hybrid Immunity. J Pediatric Infect Dis Soc. 2024 Jan 29;13(1):91-99. PMID: 38016076
Simeone RM, Zambrano LD, Halasa NB, Fleming-Dutra KE, Newhams MM, Wu MJ, Orzel-Lockwood AO, Kamidani S, Pannaraj PS, …Campbell AP, Randolph AG; Overcoming COVID-19 Investigators. Effectiveness of Maternal mRNA COVID-19 Vaccination During Pregnancy Against COVID-19-Associated Hospitalizations in Infants Aged <6 Months During SARS-CoV-2 Omicron Predominance - 20 States, March 9, 2022-May 31, 2023. MMWR Morb Mortal Wkly Rep. 2023 Sep 29;72(39):1057-1064. PMID: 37874864
Halasa N, Zambrano LD, Amarin JZ, Stewart LS, Newhams MM, Levy ER, Shein SL, Carroll CL, Fitzgerald JC, Michaels MG, Bline K, Cullimore ML, Loftis L, Montgomery VL, Jeyapalan AS, Pannaraj PS, … Randolph AG, Campbell AP; RSV-PIC Investigators. Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak. JAMA Netw Open. 2023 Aug 1;6(8):e2328950. PMID: 37581884
Habel JR, Chua BY, Kedzierski L, Selva KJ, Damelang T, Haycroft ER, Nguyen TH, Koay HF, Nicholson S, McQuilten HA, Jia X, Allen LF, Hensen L, Zhang W, van de Sandt CE, Neil JA, Pragastis K, Lau JS, Jumarang J, Allen EK, Amanant F, Krammer F, Wragg KM, Juno JA, Wheatley AK, Tan HX, Pell G, Walker S, Audsley J, Reynaldi A, Thevarajan I, Denholm JT, Subbarao K, Davenport MP, Hogarth PM, Godfrey DI, Cheng AC, Tong SY, Bond K, Williamson DA, McMahon JH, Thomas PG, Pannaraj PS, James F, Holmes NE, Smibert OC, Trubiano JA, Gordon CL, Chung AW, Whitehead CL, Kent SJ, Lappas M, Rowntree LC, Kedzierska K. Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations. JCI Insight. 2023 Apr 10;8(7):e167157. PMID: 37036008
Rowntree LC, Nguyen TH, Kedzierski L, Neeland MR, Petersen J, Crawford JC, Allen LF, Clemens EB, Chau B, McQuilten HA, Minervina AA, Pogorelyy MV, Chaurasia P, Tan HX, Wheatley AK, Jia X, Amanat F, Krammer F, Allen EK, Sonda S, Flanagan KL, Jumarang J, Pannaraj PS, Licciardi PV, Kent SJ, Bond KA, Williamson DA, Rossjohn J, Thomas PG, Tosif S, Crawford NW, van de Sandt CE, Kedzierska K. SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection. Immunity, 2022 Jul 12;55(7):1299-1315.e4. PMID: 35750048
Congrave-Wilson Z*, Cheng WA*, Lee Y, Perez S, Turner L, Marentes Ruiz CJ, Mendieta S, Skura A, Jumarang J, Del Valle J, Kubale J, Gordon A, Allen EK, Thomas PG, Pannaraj PS. Twelve-Month Longitudinal Serology in SARS-CoV-2 Naïve and Experienced Vaccine Recipients and Unvaccinated COVID-19-Infected Individuals Vaccines 2022;10(5):813. PMID: 35632569
Pannaraj PS, Costa-Martins AG, Cerini C, Li F, Wong SS, Webby RJ, Singh Y, Urbanski AH, Gonzalez-Dias P, Yang J, Nakaya H, Aldrovandi GM. Molecular alterations in human milk in simulated maternal nasal mucosal infection with live attenuated influenza vaccination. Mucosal Immunol 2022;15(5):1040-1047. PMID: 35739193
Bender JM, Lee Y, Cheng W, Marentes Ruiz CJ, Pannaraj PS. Coronavirus Disease 2019 Vaccine Booster Effects Are Seen in Human Milk Antibody Response. Front Nutr. 2022; 9:898849. PMID: 35685893
Perez S, Luna Centeno LD, Cheng W, Marentes Ruiz CJ, Congrave-Wilson Z, Powell R, Stellwagen L, Pannaraj PS. Human Milk SARS-CoV-2 Antibodies up to 6 Months After Vaccination. Pediatrics. Pediatrics. 2022:e2021054260. PMID: 34981122
Tanaka ML, Marentes Ruiz CJ, Malhotra S, Turner L, Peralta A, Lee Y, Jumarang J, Perez S, Dien Bard J, Gordon A, Allen EK, Thomas PG, Pannaraj PS. SARS-CoV-2 Transmission Dynamics in Households With Children, Los Angeles, California. Front Pediatr. 2022; 9:752993. PMID: 35071125
Rowntree LC, Nguyen TH, Kedzierski L, Neeland MR, Petersen J, Crawford JC, Allen LF, Clemens EB, Chau B, McQuilten HA, Minervina AA, Pogorelyy MV, Chaurasia P, Tan HX, Wheatley AK, Jia X, Amanat F, Krammer F, Allen EK, Sonda S, Flanagan KL, Jumarang J, Pannaraj PS, Licciardi PV, Kent SJ, Bond KA, Williamson DA, Rossjohn J, Thomas PG, Tosif S, Crawford NW, van de Sandt CE, Kedzierska K. SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection. Immunity, 2022; 55(7):1299-1315.e4. PMID: 35750048
Halasa NB, Olson SM, Staat MA, Newhams MM, Price AM, Pannaraj PS, ... Campbell AP, Randolph AG, Patel MM; Overcoming Covid-19 Investigators. Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants. N Eng J Med, 2022; 387(2):109-119. PMID: 35731908
Price AM, Olson SM, Newhams MM, Halasa NB, Boom JA, Sahni LC, Pannaraj PS, ... Zambrano LD, Campbell AP, Patel MM, Randolph AG; Overcoming Covid-19 Investigators. Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. N Engl J Med. 2022; 386(20):1899-1909. PMID: 35353976.
Congrave-Wilson Z, Lee Y, Jumarang J, Perez S, Bender J, Dien Bard J, Pannaraj PS. Change in Saliva RT-PCR Sensitivity Over the Course of SARS-CoV-2 Infection. JAMA 2021 Sep 21;326(11):1065-1067. PMID 34387653.
Kordy K, Gaufin T, Mwangi M, Li F, Cerini C, Lee DJ, Adisetiyo H, Woodward C, Pannaraj PS, Tobin NH, Aldrovandi GM. Contributions to human breast milk microbiome and enteromammary transfer of Bifidobacterium breve. PLOS One PLoS One. 2020;15(1):e0219633. PMID: 31990909
Bender JM, Li F, Purswani H, Capretz T, Cerini C, Zabih S, Hung L, Francis N, Chin S, Pannaraj PS & Aldrovandi GM. Early exposure to antibiotics in the neonatal intensive care unit alters the taxonomic and functional infant gut microbiome, J Matern Fetal Neonatal Med 2019. [Epub ahead of print].
Ho N, Li F, Lee-Sarwar K, Tun H, Brown B, Pannaraj P, Bender J, Azad M, Thompson A, Weiss S, Azcarate-Peril MA, Litonjua A, Kozyrskyj A, Jaspan H, Aldrovandi G, Kuhn L. Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations. Nature Communications. 2018; 9(1):4169. PMID: 30301893
Pannaraj PS, Ly M, Cerini C, Saavedra M, Aldrovandi GM, Saboory A, Johnson K, Pride DT. Shared and Distinct Features of Human Milk and Infant Stool Viromes. Frontiers Microbiol. 2018; 9:1162. PMID: 29910789
Pannaraj, PS, Li F, Cerini C, Bender J, Yang S, Rollie A, Adisetiyo H, Zabih S, Lincez PJ, Bittinger K, Bailey A, Bushman FD, Sleasman DJ, Aldrovandi GM. Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome. JAMA Pediatr. 2017; 171(7):647-654. PMID: 28492938